Table 5 The 15 filtered residue positions with their corresponding ConSurf values
Position | Residues | Scores of conservation | Color | Conservation levels | Buried/exposed (B/E) | Functional/structural role |
|---|---|---|---|---|---|---|
52 | C | − 0.818 | 9 | Highly conserved | Buried | Structural |
114 | C | − 0.822 | 9 | Highly conserved | Buried | Structural |
115 | D | − 0.665 | 9 | Highly conserved | Buried | Structural |
128 | G | − 0.741 | 9 | Highly conserved | Buried | Structural |
131 | C | − 0.822 | 9 | Highly conserved | Buried | Structural |
138 | V | − 0.725 | 9 | Highly conserved | Buried | Structural |
150 | C | − 0.823 | 9 | Highly conserved | Buried | Structural |
159 | G | − 0.823 | 9 | Highly conserved | Buried | Structural |
360 | G | − 0.656 | 8 | Highly conserved | Exposed | Functional |
403 | L | − 0.719 | 9 | Highly conserved | Buried | Structural |
468 | L | − 0.484 | 8 | Highly conserved | Buried | – |
480 | D | − 0.842 | 9 | Highly conserved | Exposed | Functional |
521 | Y | − 0.777 | 9 | Highly conserved | Exposed | Functional |
597 | R | − 0.797 | 9 | Highly conserved | Exposed | Functional |
643 | F | − 0.714 | 9 | Highly conserved | Buried | Structural |