Non-synonymous SNPs variants of PRKCG and its association with oncogenes predispose to hepatocellular carcinoma

Table 6 Assessing the pathogenicity of filtered nsSNPs through different softwares

Residues	FATHMM_score	FATHMM_converted_rankscore	FATHMM_pred	PROVEAN_score	PROVEAN_converted_rankscore	PROVEAN_pred
C52S	− 7.56	0.9989	D	− 7.62	0.95394	D
C114Y	− 7.56	0.9989	D	− 10.17	0.98905	D
D115Y	− 3.21	0.93291	D	− 8.14	0.96736	D
G128R	− 3.46	0.94508	D	− 7.13	0.94048	D
C131Y	− 7.56	0.9989	D	− 9.82	0.98684	D
V138M	− 3.54	0.94799	D	− 2.38	0.52451	N
C150R	− 3.27	0.98487	D	− 10.9	0.99248	D
G159R	− 0.8	0.91589	T	− 7.44	0.94872	D
G360S	− 3.98	0.96277	D	− 5.38	0.84954	D
L403P	1.3	0.3559	T	− 6.75	0.92692	D
L468P	0.73	0.50721	T	− 6.38	0.911	D
D480Y	− 3.16	0.92996	D	− 8.58	0.9743	D
Y521C	0.37	0.57729	T	− 8.59	0.97447	D
R597H	− 0.57	0.71307	T	− 4.22	0.75854	D
F643L	− 3.05	0.92407	D	− 5.54	0.86149	D

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