Fig. 6

Constuction of novel immune risk score (NIRS). A Ten-fold cross-validation of the coefficients of 37 protective genes in the LASSO regression model. B Robustness test of the LASSO model with varying number of protective genes revealed the highest stability when the number was 6, and a total of six characteristic genes were obtained. C K-M survival curve of patients with high- and low- NIRS in the TCGA-UCEC cohort, and the ordinate represented the progression-free survival (PFS). D–F K-M survival curves of patients with high- and low- NIRS in the training set, validation set and the overall cohort, and the ordinate represented the overall survival (OS). G, H Time-dependent ROC curve analysis and calibration curve of NIRS at 3-, 5-, and 7-year intervals. I Distribution plot, survival scatter plot and expression profiles of model genes in patients with high- and low- NIRS in the cohort. Red represented high expression and green represented low expression. J, K Univariate and multivariate Cox regression analyses of NIRS and key prognostic clinical features of UCEC