Fig. 8

Correlation analyses between NIRS and immune checkpoints. A The correlation matrix between 46 immune checkpoints with three system genes and NIRS expression. Yellow represented positive correlation and green represented negative correlation. B Box plots of differential expression levels of six immune checkpoints PD-1, PD-L1, CTLA-4, LAG-3, TIM-3, and TIGIT in patients with high- and low- NIRS groups