Fig. 7
From: Polyploid giant cancer cells, cytokines and cytomegalovirus in breast cancer progression
Correlation between HCMV presence and cytokines expression in PGCCs-positive breast biopsies. Pearson’s correlation between HCMV load and cytokines expression was conducted in luminal and basal breast cancer biopsies. A statistically significant strong positive correlation was observed between HCMV presence and IL-10, IL-6, all cytokines, and pro-inflammatory cytokines in PGCCs-positive basal-like biopsies. The X-axis represents cytokine expression (Ct value), and the Y -axis represents viral load as measured by IE1 qPCR (Ct value). All cytokines: TGF-β, IL-6, IL10, IL-1β, Pro-inflammatory cytokines: IL-1β and IL-6. (r) stands for correlation coefficient. *p-value ≤ 0.05; **p-value ≤ 0.01