Skip to main content
Fig. 2 | Cancer Cell International

Fig. 2

From: Exosome-derived circKIF20B suppresses gefitinib resistance and cell proliferation in non-small cell lung cancer

Fig. 2

Knockdown of circKIF20B promotes gefitinib resistance and NSCLC proliferation. A and C The effect of circKIF20B knockdown on the viability of PC9, PC9GR, HCC827, and HCC827GR were analyzed by CCK-8 assay. B and D The effect of circKIF20B knockdown on the gefitinib IC50 values of PC9, PC9GR, HCC827, and HCC827GR were analyzed by CCK-8 assay. E The cell cycle in HCC827 and HCC827GR were detected by flow cytometry. F In HCC827 and HCC827GR, the apoptosis levels of the circKIF20B-KD groups were analyzed by flow cytometry in the presence or absence of gefitinib treatment. G and H In HCC827 and HCC827GR, EdU analyzed the proliferation rate of the circKIF20B-KD groups with or without gefitinib. I and J Western blotting assays verified the BAX and CDK4 protein expression in the HCC827 circKIF20B-KD group

Back to article page

Cancer Cell International

ISSN: 1475-2867

Contact us