Skip to main content
Fig. 3 | Cancer Cell International

Fig. 3

From: Exosome-derived circKIF20B suppresses gefitinib resistance and cell proliferation in non-small cell lung cancer

Fig. 3

Overexpression of circKIF20B inhibits gefitinib resistance and proliferation of NSCLC. A and C The effect of circKIF20B overexpressed on the viability of PC9, PC9GR, HCC827, and HCC827GR were analyzed by CCK-8 assay. B and D The effect of circKIF20B overexpressed on the gefitinib IC50 values of PC9, PC9GR, HCC827, and HCC827GR were analyzed by CCK-8 assay. E With or without gefitinib, cell cycle assay of circKIF20B-OE groups was detected using flow cytometry in PC9 and PC9GR. F With or without gefitinib, the apoptosis level of the circKIF20B-OE groups was analyzed by flow cytometry in PC9 and PC9GR. G and H In PC9 and PC9GR, EdU analyzed the proliferation rate of circKIF20B-OE groups with or without gefitinib. I and J Western blot assays verified the BAX and CDK4 protein expression in the PC9 circKIF20B-OE group

Back to article page

Cancer Cell International

ISSN: 1475-2867

Contact us