Table 3 Correlation between hsa_circ_000200 expression and clinical pathological characteristic in GC serum exosomes (n = 50)
Features | Number | High | Low | P value |
|---|---|---|---|---|
Gender | ||||
Male | 39 (78%) | 20 (77%) | 19 (79%) | 0.848 |
Female | 11 (22%) | 6 (23%) | 5 (21%) | |
Age (years) | ||||
< 60 | 10 (20%) | 5 (19%) | 5 (21%) | 0.887 |
≥ 60 | 40 (80%) | 21 (81%) | 19 (79%) | |
Tumor size (cm) | ||||
< 5 | 29 (58%) | 12 (60%) | 17 (57%) | 0.815 |
≥ 5 | 21 (42%) | 8 (40%) | 13 (43%) | |
Lymphatic metastasis | ||||
N0 | 16 (32%) | 9 (28%) | 7 (39%) | 0.434 |
N1–3 | 34 (68%) | 23 (72%) | 11 (61%) | |
Distal metastasis | ||||
M0 | 45 (90%) | 20 (80%) | 25 (100%) | 0.018* |
M1 | 5 (10%) | 5 (20%) | 0 (0%) | |
Invasion depth | ||||
T1 and T2 | 12 (24%) | 4 (16%) | 8 (32%) | 0.185 |
T3 and T4 | 38 (76%) | 21 (84%) | 17 (68%) | |
TNM stage | ||||
I and II | 19 (38%) | 9 (30%) | 10 (50%) | 0.153 |
III and IV | 31 (62%) | 21 (70%) | 10 (50%) | |
CA199 | ||||
Negative | 41 (82%) | 18 (69%) | 23 (96%) | 0.014* |
Positive | 9 (18%) | 8 (31%) | 1 (4%) | |
CA125 | ||||
Negative | 42 (84%) | 19 (73%) | 23 (96%) | 0.028* |
Positive | 8 (16%) | 7 (27%) | 1 (4%) | |