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Fig. 2 | Cancer Cell International

Fig. 2

From: LncRNA LZTS1-AS1 induces proliferation, metastasis and inhibits autophagy of pancreatic cancer cells through the miR-532 /TWIST1 signaling pathway

Fig. 2

LZTS1‐AS1 promotes the proliferation and oncogenicity of PANC cells; A: LZTS1‐AS1 expression was effectively knocked down by siRNA transfection in CFPAC-1 and Capan-1 cells; B: Knockdown of LZTS1-AS1 in CFPAC-1 and Capan-1 cells significantly inhibited cell proliferation; C: Knockdown of LZTS1-AS1 in CFPAC-1 and Capan-1 cells significantly inhibited cell colony formation; D: Knockdown of LZTS1-AS1 in CFPAC-1 and Capan-1 cells resulted in cell cycle arrest at G1 phase; E: Knockdown of LZTS1-AS1 significantly inhibited the expression of Cyclin D1 and MMP-9 in CFPAC-1 and Capan-1 cells; F: Knockdown of LZTS1-AS1 in CFPAC-1 and Capan-1 cells significantly inhibited the oncogenicity of cells; *P < 0.05 and **P < 0.01 compared with si-NC

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Cancer Cell International

ISSN: 1475-2867

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