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Fig. 3 | Cancer Cell International

Fig. 3

From: LncRNA LZTS1-AS1 induces proliferation, metastasis and inhibits autophagy of pancreatic cancer cells through the miR-532 /TWIST1 signaling pathway

Fig. 3

LZTS1‐AS1 promotes migration and invasion of PANC cells, and inhibits apoptosis and autophagy; A: Knockdown of LZTS1-AS1 in CFPAC-1 and Capan-1 cells induced apoptosis; B: Knockdown of LZTS1-AS1 in CFPAC-1 and Capan-1 cells induced autophagosome formation, red arrows indicate autophagosomes; C: Knockdown of LZTS1-AS1 in CFPAC-1 and Capan-1 cells induced the expression of autophagy marker proteins; D: Knockdown of LZTS1-AS1 in CFPAC-1 and Capan-1 cells inhibited cell migration; E: Knockdown of LZTS1-AS1 in CFPAC-1 and Capan-1 cells inhibited cell invasion; F: Knockdown of LZTS1-AS1 in CFPAC-1 and Capan-1 cells inhibited the expression of EMT marker proteins; *P < 0.05 and **P < 0.01 compared with si-NC

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Cancer Cell International

ISSN: 1475-2867

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