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Fig. 5 | Cancer Cell International

Fig. 5

From: LncRNA LZTS1-AS1 induces proliferation, metastasis and inhibits autophagy of pancreatic cancer cells through the miR-532 /TWIST1 signaling pathway

Fig. 5

LZTS1‐AS1 promotes the proliferation and oncogenicity of PANC cells through sponge miR-532; A: The miR-532 inhibitor effectively knocked down the expression level of miR-532 in CFPAC-1 cells; B: Compared with LZTS1-AS1 knockdown alone, simultaneous inhibition of miR-532 significantly increased cell proliferation; C: Compared with LZTS1-AS1 knockdown alone, simultaneous inhibition of miR-532 significantly increased cell colony formation; D: Compared with LZTS1-AS1 knockdown alone, simultaneous inhibition of miR-532 significantly increased the expression of Cyclin D1 and MMP-9; E: Compared with LZTS1-AS1 knockdown alone, simultaneous inhibition of miR-532 significantly increased tumor volume and weight in nude mice; **P < 0.01, compared with si-LZTS1-AS1 + NC inhibitor

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Cancer Cell International

ISSN: 1475-2867

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