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Fig. 7 | Cancer Cell International

Fig. 7

From: LncRNA LZTS1-AS1 induces proliferation, metastasis and inhibits autophagy of pancreatic cancer cells through the miR-532 /TWIST1 signaling pathway

Fig. 7

MiR-532 negatively regulates TWIST1 expression in PANC; A: Overexpression of miR-532 in CFPAC-1 cells significantly decreased TWIST1 mRNA expression level, **P < 0.01 compared with NC mimics; B: Overexpression of miR-532 in CFPAC-1 cells significantly decreased TWIST1 protein expression level, **P < 0.01 compared with NC mimics; C: Knockdown of miR-532 in CFPAC-1 cells significantly increased TWIST1 mRNA expression level, **P < 0.01 compared with NC inhibitor; D: Knockdown of miR-532 in CFPAC-1 cells significantly increased TWIST1 protein expression level, **P < 0.01 compared with NC inhibitor; E: TWIST1 mRNA expression was significantly increased in PANC tissues, **P < 0.01 compared with Non-tumor; F: There was a negative correlation between miR-532 and TWIST1 mRNA expression in PANC tissues, r2 = 0.8755

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Cancer Cell International

ISSN: 1475-2867

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