Skip to main content
Fig. 9 | Cancer Cell International

Fig. 9

From: LncRNA LZTS1-AS1 induces proliferation, metastasis and inhibits autophagy of pancreatic cancer cells through the miR-532 /TWIST1 signaling pathway

Fig. 9

MiR-532 inhibits PANC cell migration and invasion and induces apoptosis and autophagy by negatively regulating TWIST1; A: Overexpression of TWIST1 reversed the induction of apoptosis by miR-532; B: Overexpression of TWIST1 reversed the induction of autophagy by miR-532; C: Overexpression of TWIST1 reversed the induction of expression of autophagy marker proteins by miR-532; D: Overexpression of TWIST1 reversed the inhibition of miR-532 on the migration of cells; E: Overexpression of TWIST1 reversed the inhibition of miR-532 on the invasion of cell; F: Overexpression of TWIST1 reversed the inhibition of miR-532 on the expression of EMT marker proteins; *P < 0.05 and **P < 0.01 compared with NC mimics + pcDNA3.1, #P < 0.05 and ##P < 0.01 compared with miR-532 mimics + pcDNA3.1

Back to article page

Cancer Cell International

ISSN: 1475-2867

Contact us