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Fig. 5 | Cancer Cell International

Fig. 5

From: Tumor-derived small extracellular vesicles promote breast cancer progression by upregulating PD-L1 expression in macrophages

Fig. 5

Screening miRNAs in enriched plasma sEVs of metastatic BC patients. (A) Heat map of differential expression of miRNAs among group N, group E and group A. (B-D) Disease enrichment analysis, functional enrichment analysis, and target genes analysis of differential expression miRNA among the three groups. (E-F) GO functional annotation analysis and KEGG pathway analysis of differential expression miRNA target genes among the three groups. (G) The differential expression of miRNAs in plasma sEVs among the three groups verified by RT-qPCR.

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