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Fig. 2 | Cancer Cell International

Fig. 2

From: The effect of matrices on the gene expression profile of patient-derived head and neck carcinoma cells for in vitro therapy testing

Fig. 2

Patient-derived cells cultured in different culturing conditions express significantly up- and downregulated pathways. Results of the gene set enrichment analysis (GSEA) show up- and downregulated pathways in patient-derived cells cultured in different matrices. (A) Plastic in comparison with fresh tissue sample, (B) Matrigel in comparison with fresh tissue sample, (C) Myogel in comparison with fresh tissue sample, (D) Plastic in comparison with freshly digested single cells, (E) Matrigel in comparison with freshly digested single cells, (F) Myogel in comparison with freshly digested single cells, (G) Matrigel in comparison with plastic, (H) Myogel in comparison with plastic, (I) Myogel in comparison with Matrigel. NES, normalized enrichment score

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