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Fig. 5 | Cancer Cell International

Fig. 5

From: The effect of matrices on the gene expression profile of patient-derived head and neck carcinoma cells for in vitro therapy testing

Fig. 5

Culturing patient-derived cells affect the expression of some MMP and collagen genes. Differential expression (DE) analysis from RNA sequencing transcriptome profile revealed significant changes in the expression of genes in all culturing conditions compared to fresh tissue sample and freshly isolated cancer cells. (A) Three MMP genes were downregulated in cultured cells. (B) Four collagen genes were downregulated in cultured cells. The genes that passed the filter criteria had a p < 0.05. The mean is presented as a red box and the median as a black line

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Cancer Cell International

ISSN: 1475-2867

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