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Fig. 7 | Cancer Cell International

Fig. 7

From: The effect of matrices on the gene expression profile of patient-derived head and neck carcinoma cells for in vitro therapy testing

Fig. 7

Culturing patient-derived cells affect the expression of genes in TNF superfamily and TNF receptor superfamily. Differential expression (DE) analysis from RNA sequencing transcriptome profile revealed significant changes in the expression of genes in TNE superfamily and TNF receptor superfamily in all culturing conditions compared to both fresh tissue sample and freshly isolated single cells. All TNF superfamily genes were downregulated. In the TNF receptor superfamily two genes were downregulated and three upregulated. The genes that passed the filter criteria had a p < 0.05. The mean is presented as a red box and the median as a black line

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Cancer Cell International

ISSN: 1475-2867

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