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Fig. 1 | Cancer Cell International

Fig. 1

From: A novel quinoline derivative, DFIQ, sensitizes NSCLC cells to ferroptosis by promoting oxidative stress accompanied by autophagic dysfunction and mitochondrial damage

Fig. 1

DFIQ sensitized NSCLC cells to FIs and promoted ferroptosis. a IC50 alterations of FIs after DFIQ treatment. n = 4. b and c Western blot analysis of ferroptosis-associated protein expression after DFIQ and FI (erastin b and RSL3 c) treatment in H1299 cell lines. d Changes in the viability of H1299 and H460 cells cotreated with DFIQ/RSL3 and the ferroptosis inhibitor liproxstatin-1. **p < 0.01 compared to the control groups, ##p < 0.01 compared with RSL3 only groups

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Cancer Cell International

ISSN: 1475-2867

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