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Fig. 1 | Cancer Cell International

Fig. 1

From: Lnc-LRRTM4 promotes proliferation, metastasis and EMT of colorectal cancer through activating LRRTM4 transcription

Fig. 1

Lnc-LRRTM4 is highly expressed in CRC and predicts poor prognosis. (A) Hierarchical clustering showing significantly differentially expressed lncRNAs of CRC tissues and para-tumor tissues from the GEO database (GSE156732) (FC ≥ 4 or ≤ -4, p < 0.05). (B) The relative expression of lnc-LRRTM4 in CRC tissues and normal tissues from TCGA database. (C) The relative expression of lnc-LRRTM4 in 50 pairs of CRC tissues and corresponding para-tumor tissues. (D) The expression of lnc-LRRTM4 in normal intestinal epithelial cell line FHC and CRC cell lines (HCT116, SW480, DLD1, LoVo, HCT8, SW620 and HT29). (E) Kaplan–Meier analysis of the OS rate in CRC patients in the TCGA database with high or low expression of lnc-LRRTM4. (F) Kaplan–Meier analysis of the DFS rate in CRC patients in the TCGA database with high or low expression of lnc-LRRTM4. Data are the means ± SD (n = 3 independent experiments), ** p < 0.01, *** p < 0.001

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Cancer Cell International

ISSN: 1475-2867

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