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Fig. 7 | Cancer Cell International

Fig. 7

From: Lnc-LRRTM4 promotes proliferation, metastasis and EMT of colorectal cancer through activating LRRTM4 transcription

Fig. 7

LRRTM4 is essential for Lnc-LRRTM4-mediated cell proliferation and metastasis. (A) The effects of LRRTM4 overexpression on cell cycle in lnc-LRRTM4 stable knockdown HCT116 and SW480 cells and the effects of LRRTM4 inhibition on cell cycle in lnc-LRRTM4 overexpression LoVo cells. (B) The effects of LRRTM4 overexpression on apoptosis in lnc-LRRTM4 stable knockdown HCT116 and SW480 cells and the effects of LRRTM4 inhibition on apoptosis in lnc-LRRTM4 overexpression LoVo cells. (C) The effects of LRRTM4 overexpression on cell cycle proteins and apoptosis proteins in lnc-LRRTM4 stable knockdown HCT116 and SW480 cells and the effects of LRRTM4 inhibition on cell cycle proteins and apoptosis proteins in lnc-LRRTM4 overexpression LoVo cells. (D) The effects of LRRTM4 overexpression on EMT proteins in lnc-LRRTM4 stable knockdown HCT116 and SW480 cells and the effects of LRRTM4 inhibition on EMT proteins in lnc-LRRTM4 overexpression LoVo cells. Data are the means ± SD (n = 3 independent experiments), * p < 0.05, ** p < 0.01, *** p < 0.001

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Cancer Cell International

ISSN: 1475-2867

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