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Fig. 4 | Cancer Cell International

Fig. 4

From: Regulatory role of Chitinase 3-like 1 gene in papillary thyroid carcinoma proved by integration analyses of single-cell sequencing with cohort and experimental validations

Fig. 4

The Epi02 epithelial subcluster stands as one of the important cell clusters for malignant development of PTC. (B, C) Subcluster Epi02. (A, D, E, F) All epithelial lineages covering all five epithelial subclusters. (A) Pseudotime trajectory analysis of all five epithelial subclusters. (B) The fold change value of CHI3L1 is highest among differentially expressed genes in epithelial subcluster Epi02 between PTC1 and PTC2. (C) KEGG pathway analysis of different genes in epithelial subcluster Epi02 between PTC1 and PTC2. (D-F) The expression of CHI3L1, COL1A1, and CXCL14 in epithelial lineages between PTC1 and PTC2

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Cancer Cell International

ISSN: 1475-2867

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