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Fig. 6 | Cancer Cell International

Fig. 6

From: Regulatory role of Chitinase 3-like 1 gene in papillary thyroid carcinoma proved by integration analyses of single-cell sequencing with cohort and experimental validations

Fig. 6

CHI3L1 promotes proliferation, invasion, and metastasis in TPC-1 cells. TPC-1 cells overexpressing CHI3L1 (OE-CHI3L1) or with CHI3L1 knockdown (CHI3L1 shRNA) were included. pcDNA3flag and pmRZip empty plasmid were used as controls. (A-B) Expression. (C) Cell proliferation. (D-E) Cell invasion. (F-G) Cell metastasis. Scale bar, 8 μm. In the bar charts, different lowercase letters indicate significant differences (P < 0.05)

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