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Table 1 The relationship between the expression level of CHI3L1 protein and the Clinical features of 110 patients with PTC

From: Regulatory role of Chitinase 3-like 1 gene in papillary thyroid carcinoma proved by integration analyses of single-cell sequencing with cohort and experimental validations

Clinical features

Number of

Expression level of CHI3L1

χ2

P-value

cases

Low/None

High

Sex

Male

23

14(61%)

9(39%)

0.096

0.756

 

Female

87

56(64%)

31(36%)

  

Age

< 55

74

53(72%)

21(28%)

6.231

0.013

 

≥ 55

36

17(47%)

19(53%)

  

T stage

T1

29

27(93%)

2(7%)

29.661

< 0.001

T2

24

18(75%)

6(25%)

  

T3

25

16(64%)

9(36%)

  

T4

32

9(28%)

23(72%)

  

N stage

N0

41

39(95%)

2(5%)

29.981

< 0.001

N1a

11

7(64%)

4(36%)

  

N1b

58

24(41%)

34(59%)

  

M stage

M0

101

68(67%)

33(33%)

7.265

0.007

M1

9

2(22%)

7(78%)

  

Gross ETE*

No

51

43(84%)

8(16%)

17.568

< 0.001

Yes

59

27(46%)

32(54%)

  

BRAFV600E

Mut

90

58(64%)

32(36%)

0.140

0.709

Wildtype

20

12(60%)

8(40%)

  
  1. * Gross Extrathyroidal extension (ETE): invading the subcutaneous soft tissues, larynx, trachea, esophagus, or recurrent laryngeal nerve (RLN)
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Cancer Cell International

ISSN: 1475-2867

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