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Fig. 1 | Cancer Cell International

Fig. 1

From: ITC-6102RO, a novel B7-H3 antibody-drug conjugate, exhibits potent therapeutic effects against B7-H3 expressing solid tumors

Fig. 1

Characteristics of ITC-6102RO. (A) Composition of the ADC. (B) Binding affinity between antibody and ADC. BLI kinetic assays were performed using an Octet QKE biosensor by first capturing 10-µg/ml antibodies with anti-human Fc (AHC) biosensors, followed by a 300 s baseline step in kinetic buffer. Binding sensorgrams were obtained using the 8-channel detection mode on the Octet QKE unit

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