Fig. 4From: ITC-6102RO, a novel B7-H3 antibody-drug conjugate, exhibits potent therapeutic effects against B7-H3 expressing solid tumorsPK profiles of ITC-6102RO. (A) In rats, the pharmacokinetic profiles of tAb (total antibody) and acDrug (antibody-conjugated drug) after intravenous administration of 3Â mg/kg ITC-6102RO. (B) The drug-antibody ratio (DAR) profiles in rat plasma for ITC-6102RO. The number of conjugated linker drugs per antibody was quantified using HIC-HPLC analysisBack to article page