Skip to main content
Fig. 4 | Cancer Cell International

Fig. 4

From: Elevated levels of neutrophil related chemokine citrullinated histone H3, interleukin-8 and C-reaction protein in patients with immune checkpoint inhibitor therapy: predictive biomarkers for response to treatment

Fig. 4

Development and validation of the prediction nomogram in the primary cohort. (A) Nomogram to predict the response in patients with ICI therapy. The nomogram is valued to obtain the probability of the ICI response by adding up the points identified on the points scale for each variable, which included the level of H3Cit, IL-8 and CRP. (B) Calibration curve of our nomogram. (C) The AUC of our nomogram was 0.937 (95% CI: 0.886–0.988, P < 0.001). (D) The results of the decision curve analysis. Decision curve analysis for the nomogram and other previously reported variables. The gray line represents the assumption that all patients are within the responder group. The thin black line represents the assumption that all patients are within the nonresponder group

Back to article page

Cancer Cell International

ISSN: 1475-2867

Contact us