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Fig. 1 | Cancer Cell International

Fig. 1

From: Knockdown of TFRC suppressed the progression of nasopharyngeal carcinoma by downregulating the PI3K/Akt/mTOR pathway

Fig. 1

TfR was upregulated in cancers, including nasopharyngeal carcinoma (NPC). (A) GEPIA database showed TFRC was widely upregulated in most cancer types, including head and neck squamous carcinoma (HNSC). (B) High TFRC expression in HNSC patients is associated with shorter overall survival. (C) TFRC was upregulated in NPC tissues than control tissues in four NPC GEO datasets. (D) TFRC was upregulated in 9 NPC cell lines than normal nasopharyngeal epithelial cell line NP69, as assessed by RT-qPCR. (E) TfR was upregulated in NPC tissues by IHC. Asterisks indicate *p < 0.05, ***p < 0.001 compared to control

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Cancer Cell International

ISSN: 1475-2867

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