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Fig. 3 | Cancer Cell International

Fig. 3

From: Knockdown of TFRC suppressed the progression of nasopharyngeal carcinoma by downregulating the PI3K/Akt/mTOR pathway

Fig. 3

Knockdown of TFRC inhibited cell migration, invasion, and epithelial–mesenchymal transition in vitro. (A) Representative images from wound healing assays showing knockdown of TFRC suppressed cell migration. (B) Summary bar graph showing percentage wound closure in TFRC knockdown group is lower than that in the control group at the 6 and 24 h time points. (C) Representative images of the invasion assay. (D) Summary bar graph showing the invaded cells in the TFRC knockdown cells as less than that in the control cells. (E-G) Knockdown of TFRC inhibits Vimentin and N-cadherin (mesenchymal phenotype), and increases E-cadherin (epithelial phenotype). The results are given for three independent experiments. Asterisks indicate *p < 0.05, **p < 0.01, ***p < 0.001 compared to control

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Cancer Cell International

ISSN: 1475-2867

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