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Fig. 5 | Cancer Cell International

Fig. 5

From: Knockdown of TFRC suppressed the progression of nasopharyngeal carcinoma by downregulating the PI3K/Akt/mTOR pathway

Fig. 5

RNA sequencing analysis after TFRC knockdown in HK1-EBV cells. (A) mRNA level of TFRC  was significantly decreased in siTFRC#2-HK1-EBV samples, as assessed by RT-qPCR. (B) Proportion pie chart showing GO analysis of altered biological process after knockdown of TFRC, using DAVID database. (C) Proportion pie chart showed altering pathways after knockdown of TFRC, using KEGG data from DAVID database. (D) Knockdown of TFRC inhibited the phospho-Akt (p-Akt) level, which is the PI3K-Akt signaling pathway marker. (E) Knockdown of TFRC inhibited the mTOR level. The results are given for three independent experiments. Asterisks indicate *p < 0.05 compared to control

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