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Fig. 6 | Cancer Cell International

Fig. 6

From: Knockdown of TFRC suppressed the progression of nasopharyngeal carcinoma by downregulating the PI3K/Akt/mTOR pathway

Fig. 6

Schematic diagram of the proposed mechanisms. TfR was overexpressed in NPC tissues and cells. Knockdown of TFRC led to iron deprivation and inhibited cell proliferation, migration, invasion, and EMT, which may function by inhibiting the activity of the PI3K/Akt/mTOR signaling pathway. TFRC participates in NPC development and may serve as a novel biomarker and therapeutic target for NPC.

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Cancer Cell International

ISSN: 1475-2867

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