Fig. 2
From: Natural killer cell-derived exosomes for cancer immunotherapy: innovative therapeutics art
Exosome biogenesis process. The whole procedure of exosome biogenesis from source to delivery. Start with the internalization of proteins and lipid complexes; then continued with the inward budding of endosomes which pack and transport cargoes inside multivesicular bodies (MVB). finally, Exos are released from the cells which can be used for treatment after isolating and characterizing. NK, natural killer; IL, interleukin; mAb, monoclonal antibody; CAR NK, chimeric antigen receptor-natural killer