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Table 5 IC50 values of gilteritinib and abemaciclib measured in AML cell lines

From: Combination strategies to overcome drug resistance in FLT+ acute myeloid leukaemia

 

Gilteritinib (nM)

Abemaciclib (µM)

MOLM-13

0.99 ± 0.14

0.53 ± 0.18

MOLM-14

3.60 ± 0.04

0.24 ± 0.17

MV4-11

1.85 ± 0.06

3.83 ± 0.09

  1. Numerical IC50 values were calculated with non-linear best-fit regression analysis using the Prism 8 software. See Additional file 1: Figs. S12 and S13 for concentration-dependent normalised cell viabilities