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Fig. 1 | Cancer Cell International

Fig. 1

From: Using integrated analysis from multicentre studies to identify RNA methylation-related lncRNA risk stratification systems for glioma

Fig. 1

Construction of an RNA methylation-related lncRNA signature based on DE-m6A/m5C/m1A score-related lncRNAs associated with the survival of glioma patients. A Analysis of network topology for various soft-thresholding powers. B Gene dendrogram with different colours showing modules identified by WGCNA. C Relationship between gene modules and different m6A/m5C/m1A scores of gliomas. D Volcano plot of DE-lncRNAs between the normal and glioma groups in the TCGA database (selection criteria: P < 0.05 and |log2 FC|> 0.5). E Venn diagrams of RNA methylation-related lncRNAs by taking the intersections of significantly upregulated and downregulated DE-lncRNAs and m6A/m5C/m1A score-related lncRNAs. F, G The results of univariate Cox regression analysis (F) and multivariate Cox regression analysis (G) for the RNA methylation-related lncRNAs significantly associated with glioma OS. DE-RNA differentially expressed RNA, WGCNA weighted gene co-expression network analysis, TCGA The Cancer Genome Atlas, OS overall survival

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