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Fig. 7 | Cancer Cell International

Fig. 7

From: Using integrated analysis from multicentre studies to identify RNA methylation-related lncRNA risk stratification systems for glioma

Fig. 7

Knockdown of RP11-98I9.4 and RP11-752G15.8 promotes TMZ resistance in glioma cells. A CCK-8 assay was used to reveal the effect of RP11-98I9.4 and RP11-752G15.8 knockdown on glioma cells treated with TMZ at the indicated concentrations for 72 h. B Representative bioluminescence images of intracranial xenografts bearing LN229_shRP11-98I9.4, LN229_shRP11-752G15.8 or LN229_Scramble cells in DMSO or the presence of TMZ treatment on the indicated days. C, D Tumour volume was detected in each mouse group. E, F Kaplan‒Meier survival curve of each group is shown. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001

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Cancer Cell International

ISSN: 1475-2867

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