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Fig. 3 | Cancer Cell International

Fig. 3

From: EZH2-mediated epigenetic silencing of tumor-suppressive let-7c/miR-99a cluster by hepatitis B virus X antigen enhances hepatocellular carcinoma progression and metastasis

Fig. 3

The profile of miRNAs downregulated by HBx. A. Heatmap of 72 miRNAs that were differentially expressed in six HBV-related HCC tumors (case number 3, 13, 48, 58, 60, 68) as compared with their non-tumor tissue controls. qRT-PCR analysis of these three miRNAs was performed B in the HCC tumor (T) and non-tumor (N) tissue samples and C in HepG2X and D in Hep3BX cells as compared with the parental cells HepG2 (G2) and Hep3B (3B), respectively. E. The overall survival of let-7c, mir-199a-3p, and mir-99a in HCC patients from TCGA database

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Cancer Cell International

ISSN: 1475-2867

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