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Fig. 6 | Cancer Cell International

Fig. 6

From: EZH2-mediated epigenetic silencing of tumor-suppressive let-7c/miR-99a cluster by hepatitis B virus X antigen enhances hepatocellular carcinoma progression and metastasis

Fig. 6

HMGA2 is a target of let-7c. A, B. The comparative HMGA2 protein levels in HepG2X and Hep3BX cells 48 h after transfection with the let-7c mimic or the miRNA mimic control (negative control, NC). α-Tubulin was adopted as the endogenous control. C, D. Differential expression of HMGA2 mRNA and protein was characterized in HepG2, HepG2X, Hep3B, and Hep3BX cells. E EZH2 was transfected into HepG2 and Hep3B cells. HMGA2 expression, which was measured using qRT-PCR, was normalized against β-actin

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Cancer Cell International

ISSN: 1475-2867

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