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Table 1 Distribution of HPV infection, HPV risk groups, and single/multiple HPV infections among individuals with different cervical cytology grades

From: Type distribution of human papillomaviruses in ThinPrep cytology samples and HPV16/18 E6 gene variations in FFPE cervical cancer specimens in Fars province, Iran

 

Cervical cytology

P-value

Normal

ASC-US

ASC-H

LSIL

HSIL

 
 

N (%)

HPV test

 HPV positive

229 (48.9)

88 (93.6)

42 (100)

28 (100)

16 (100)

P < 0.0001

 HPV negative

239 (51.1)

6 (6.4)

0

0

0

Risk group

 High-risk only

35 (15.3)

12 (13.6)

12 (28.6)

8 (28.6)

0

P < 0.0001

 Possible high-risk only

12 (5.2)

0

0

0

0

 Low-risk only

135 (59.0)

2 (2.3)

0

0

0

 Multiple risk groups

47 (20.5)

74 (84.1)

30 (75.0)

20 (71.4)

16 (100)

Single/multiple infection

 

 Single infection

153 (66.8)

8 (9.1)

7 (16.7)

4 (14.3)

0

P < 0.0001

 Double infection

51 (22.3)

38 (43.2)

12 (28.6)

5 (17.9)

1 (6.3)

 Triple infection

16 (7.0)

27 (30.7)

19 (45.2)

7 (25.0)

5 (31.3)

 Quadruple infection

3 (1.3)

9 (10.2)

0

5 (17.9)

3 (18.8)

 Quintuple infection

5 (2.2)

0

3 (7.1)

1 (3.6)

4 (25.0)

 Sextuple infection

0

3 (3.4)

0

2 (7.1)

3 (18.8)

 Septuple infection

1 (0.4)

1 (1.1)

0

3 (10.7)

0

 Octuple infection

0

1 (1.1)

1 (2.4)

1 (3.6)

0

 Decuple infection

0

1 (1.1)

0

0

0