Table 1 Approved monoclonal antibodies for skin cancer treatment by FDA
From: Current status of skin cancers with a focus on immunology and immunotherapy
Approved mABs | Mechanism | Type of SC | Other forms |
|---|---|---|---|
Cemiplimab-rwlc | Anti PD-1 | Basal Cell Carcinoma Cutaneous Squamous Cell Carcinoma | Libtayo |
Pembrolizumab | Anti PD-1 | Cutaneous Squamous Cell Carcinoma Melanoma Merkel Cell Carcinoma | Keytruda |
Ipilimumab | Blocks CTLA-4 | Melanoma | Yervoy |
Nivolumab | Anti PD-1 | Melanoma | Opdivo |
Avelumab | Anti PD-1 | Metastatic Merkel cell carcinoma | – |
Cetuximab (chimeric) | Anti PD-1 | Advanced non melanoma skin cancer | – |