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Fig. 1 | Cancer Cell International

Fig. 1

From: Enhancing prognostic accuracy in head and neck squamous cell carcinoma chemotherapy via a lipid metabolism-related clustered polygenic model

Fig. 1

Lipid metabolism-related genes were significantly enriched in CRISPR/cas9 library screening. A, Illustration of the stepwise study design. B, Illustration of CRISPR/cas9 library screening in the HNSCC cell lines Fadu and Detroit 562 cells. C, Venn diagrams showing the 6,848 candidate genes related to drug resistance. D-G, GO and KEGG enrichment analyses for cisplatin and 5-FU drug screening in Fadu and Detroit 562 cells. H, PPI network analysis of the screening for differentially expressed lipid metabolism genes. I, Heatmap for differentially expressed genes involved in lipid metabolism across the four screening groups

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