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Fig. 6 | Cancer Cell International

Fig. 6

From: The novel oncogenic factor TET3 combines with AHR to promote thyroid cancer lymphangiogenesis via the HIF-1α/VEGF signaling pathway

Fig. 6

Blocking HIF-1α impairs THCA cells’ movements, migration and invasion abilities. AB BCPAP/CAY10585 and BHT101/CAY10585 cells were less motile at 24 h compared with BCPAP/parental and BCPAP/ctrl, and BHT101/parental and BHT101/ctrl cells. C.D. Wound size in BCPAP/CAY10585 and BHT101/CAY10585, BCPAP/parental and BCPAP/ctrl, and BHT101/parental and BHT101/ctrl cells (*P < 0.05). E.F. BCPAP/CAY10585 and BHT101/CAY10585 cells exhibited reduced movement through Matrigel compared to BCPAP/parental and BCPAP/ctrl, as well as BHT101/parental and BHT101/ctrl cells. G.H. Cell number in every field in BCPAP/CAY10585 and BHT101/CAY10585, BCPAP/parental and BCPAP/ctrl, and BHT101/parental and BHT101/ctrl cells (*P < 0.05, **P < 0.01)

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Cancer Cell International

ISSN: 1475-2867

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