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Fig. 2 | Cancer Cell International

Fig. 2

From: MiRNA-related metastasis in oral cancer: moving and shaking

Fig. 2

Regulation of EMT activation by miR-153-3p and WISP-1. WNT1-inducible-signaling pathway protein 1 (WISP-1) promotes the activation of EMT by upregulating Snail expression and regulating the integrin αvβ3/FAK/ILK/Akt signaling pathway. MiR-153-3p inhibits OSCC cell EMT and metastasis by targeting Snail, in return WISP-1 and induces metastasis [80]

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