Fig. 8
From: Triple negative breast cancer metastasis is hindered by a peptide antagonist of F11R/JAM‑A protein
The F11R/JAM-A antagonistic peptide (P4D) impairs the metastasis in 4T1 mouse breast cancer model. A: Effect of P4D peptide on number of metastases in liver and lungs from 4T1 mice. B: Area of largest metastasis in liver and lungs from control 4T1 mice and mice treated with two concentrations of P4D. C: Effect of P4D on number of mice with metastases observed macroscopically and microscopically in liver and in lungs. D: Number of metastases in hot spot foci in liver and lungs from breast cancer bearing mice treated or not treated with P4D. E: Area of hot spot foci with metastases in liver and in lungs from 4T1 mice treated or not treated with P4D