Fig. 5

The m5C status was different between the high- and low-risk groups and functional annotation of the two risk groups. A Principal component analysis (PCA) was performed for the low- and high-risk groups based on the whole genome and m5C-related coding genes, and a risk model was constructed using 11 m5C-related lncRNAs. B Top enriched gene pathways in low- and high-risk groups from the CRC cohort were assessed by using the GSEA algorithm. C GSVA enrichment analysis between the low- and high-risk clusters, and yellow represents activated and blue represents repressive pathways