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Fig. 4 | Cancer Cell International

Fig. 4

From: Hsa_circRNA_102051 regulates colorectal cancer proliferation and metastasis by mediating Notch pathway

Fig. 4

Hsa_circRNA_102051 enhanced stemness of CRC cells. (A) Western blot of SOX9, OCT-4 and CD44 in SW480 and HT-29 cells with different treatment. (B) QRT-PCR of SOX9, OCT-4 and CD44 in SW480 and HT-29 cells with different treatment.Expression levels of SOX9, OCT-4 and CD44 were all decreased by si-hsa_circRNA_102051 while increased by additional hsa_circRNA_102051. (C) In-vitro tumor sphere formation assays in four groups of SW480/HT-29 cells. Tumor formation was activated by hsa_circRNA_102051 while suppressed by si-circ treatment. Compared to NC or si-NC group, *P < 0.05

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Cancer Cell International

ISSN: 1475-2867

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