Fig. 7

Hsa_circRNA_102051 influenced CRC cell abilities via regulating miR-203a/BPTF. (A) CCK-8 testing in CRC cells respectively transfected with vector, hsa_circRNA_102051, miR-203a, or hsa_circRNA_102051 plus miR-203a. Hsa_circRNA_102051 overexpression enhanced CRC cell viability while miR-203a inhibited it, which got reversed in cells treated with hsa_circRNA_102051 plus miR-203a. (B) EdU assays in CRC cells with different transfections. The proliferation of CRC cells was enhanced with additional hsa_circRNA_102051 while suppressed with miR-203a, and both were reversed in the hsa_circRNA_102051 plus miR-203a group. (C) TUNEL fluorescence assay in CRC cells with different treatments. The apoptosis of CRC cells was inhibited by hsa_circRNA_102051 while triggered by miR-203a, and both were reversed in those treated with hsa_circRNA_102051 plus miR-203a. (D) Cell invasion in CRC cell lines with different transfections. Cell invasion was promoted by hsa_circRNA_102051 while inhibited by miR-203a. The hsa_circRNA_102051 plus miR-203a group had similar invasion to the control. Compared to NC group, ^*P < 0.05