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Fig. 1 | Cancer Cell International

Fig. 1

From: Progranulin promoted the proliferation, metastasis, and suppressed apoptosis via JAK2-STAT3/4 signaling pathway in papillary thyroid carcinoma

Fig. 1

Expression of PGRN in papillary thyroid carcinoma (PTC) tissues and PTC cells. (A) Expression of PGRN in PTC and normal tissues adjacent to cancer was detected by using western blotting (n = 70 per group). Relative grayscale values of PGRN in PTC tissues and normal tissues adjacent to cancer. (B) Expression of PGRN in papillary thyroid carcinoma (PTC) tissues and normal tissues adjacent to cancer was detected by qRT-PCR (n = 70 per group). (C) Expression of PGRN in PTC samples (×200, low right ×400). (a) Negative expression of PGRN in normal tissues adjacent to cancer; (b) Positive expression of PGRN in normal tissues adjacent to cancer; (c) Positive expression of PGRN in PTC tissues; (D) Representative images and quantitation of the western blotting showed that the protein expression of PGRN in the PTC cell lines (K1、TPC1 and BCPAP) and normal thyroid epithelial cells (N3) (n = 3). GAPDH was used as an internal control. (E) The relative PGRN mRNA expression in PTC cell lines and normal thyroid epithelial cell (n = 3). Data are presented as mean ± SEM. *, P < 0.05; **, P < 0.01; ***, P < 0.001

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Cancer Cell International

ISSN: 1475-2867

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