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Fig. 2 | Cancer Cell International

Fig. 2

From: MALAT1/ mir-1-3p mediated BRF2 expression promotes HCC progression via inhibiting the LKB1/AMPK signaling pathway

Fig. 2

MALAT1 promotes the proliferation, migration, invasion and anti-apoptosis of HCC cells. (a, b) The transfection efficiency of ASO-MALAT1 in Huh7 and Hep3B cells was detected by qRT-PCR. (c, d) After silencing MALAT1, cell viability of Huh7 and Hep3B cells was detected by CCK-8 assay on days 0, 1, 2, 3, 4 and 5. (e, f) Transwell assay was used to detect migration and invasion of hepatocellular carcinoma cells after MALAT1 down-regulation. (g) The apoptosis rate of HCC cells after MALAT1 knockdown was detected by flow cytometry. (h) Western blot analysis was performed to detect the expression levels of apoptosis-related proteins in HCC cells after MALAT1 knockdown. ** P < 0.01, *** P < 0.001

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Cancer Cell International

ISSN: 1475-2867

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