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Table 1 Statistics for BRF2 and clinicopathologic features in HCC patients

From: MALAT1/ mir-1-3p mediated BRF2 expression promotes HCC progression via inhibiting the LKB1/AMPK signaling pathway

 

Expression

χ2

P value

Total (n = 200)

Low(n = 100)

High(n = 100)

Age (years)

   

0.501

0.479

≤ 50

95

45

50

  

> 50

105

55

50

  

Sex

   

0.038

0.845

Male

169

84

85

  

Female

31

16

15

  

Tumour size (cm)

   

37.729

< 0.001

≤ 5

133

87

46

  

> 5

67

13

54

  

Tumour number

   

1.452

0.228

1

157

82

75

  

≥ 2

43

18

25

  

Tumour differentiation

   

0.439

0.508

I-II

152

74

78

  

III-IV

48

26

22

  

Vascular invasion

   

3.712

0.054

No

159

85

74

  

Yes

41

15

26

  

Tumour capsule

   

2.642

0.104

Yes

71

30

41

  

No

129

70

59

  

Liver cirrhosis

   

0.567

0.451

No

34

15

19

  

Yes

166

85

81

  

AFP (ng/ml)

   

0.343

0.558

≤ 400

74

39

61

  

> 400

126

35

65

  

HBsAg

   

0.767

0.381

Negative

41

18

23

  

Positive

159

82

77

  

Recurrence

   

4.522

0.033

No

93

54

39

  

Yes

107

46

61

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