Table 1 The role of PTCSC3 in different cancers

TC

10 paired tissues

PTC − 1, Nthy-ori3-1

Down

Proliferation ↓, Migration ↓

Tumor growth ↓

PTCSC3/miR-5745p/SCAI/Wnt/β catenin

(17)

TC

73 paired tissues

BCPAP, TPC-1

Down

Invasion ↓, Motility ↓

PTCSC3/ S100A4/VEGF/ MMP-9

(12)

TC

-

BCPAP, FTC133, 8505 C

Down

Growth ↓, Cell cycle ↓, Apoptosis ↑

PTCSC3/miR-574-5p.

(11)

TC

20 paired tissues

8505 C, FTC 238, FTC 133

Down

Drug resistance ↓

PTCSC3/ STAT3/ INO80

(13)

TC

68 paired tissues

PTC − 1, Nthy-ori3 -1, BCPAP

Down

Aerobic glycolysis↓, Proliferation ↓

Tumor growth ↓

PTCSC3/ PGK1

(18)

TC

-

SW579, TPC-1, BCPAP, K1, Nthy-ori3 -1

Down

Proliferation ↓, Invasion ↓ Migration ↓, Angiogenesis ↓

PTCSC3/ S100A4

(19)

GC

78 paired tissues

SNU-1, Hs 746T

Down

Proliferation ↓ Stemness↓

PTCSC3/ lncRNA Linc-pint

(25)

GC

68 cases and 60 controls

SNU-1, AGS

Down

Proliferation ↓, Invasion ↓

Migration ↓

-

(23)

GC

80 paired tissues

AGS, SNU-1

Down

Migration ↓, Invasion ↓

PTCSC3/ lncRNA HOXA11-AS

(22)

GC

77 paired tissues

SNU-1, AGS

Down

Invasion ↓, Migration ↓

PTCSC3/ HULC/ Wnt

(20)

CC

40 paired tissues

Caski, Siha, Hela, C4-1

Down

Proliferation ↓, Invasion ↓

PTCSC3/ miR-574-5p

(37)

CC

30 paired tissues

Hela, C-33 A

Down

Proliferation ↓, Invasion ↓

Migration ↓

PTCSC3/ miR-574-5p

(36)

TNBC

69 paired tissues

BT-549, HCC70

Down

Proliferation ↓

PTCSC3/LncRNA H19

(34)

OC

15 paired tissues

SCC-4, SCC-9

SCC-15, SCC-25

Down

Proliferation ↓, Invasion ↓

Apoptosis ↑

PTCSC3/ Bax, Bcl-2

PTCSC3/ LC3B-I, Beclin 1

(38)

LSCC

66 cases, 52 controls

UM-SCC-17 A

Down

Proliferation ↓

PTCSC3/ LncRNA HOTAIR

PTCSC3/STAT3

(31)

Glioma

-

U251,U87, SHG44, SHG139

Down

Proliferation ↓, Invasion ↓

Migration ↓, EMT ↓

PTCSC3/LRP6/Wnt

(40)