Fig. 4

HK3 expression in stratified glioma. (A) HK3 expression in tumors of different grades in the TCGA datasets. (B) HK3 expression in LGG stratified according to IDH mutation status in TCGA datasets. C and D. HK3 expression in GBM according to IDH mutation status and MGMT methylation status in TCGA datasets. E. HK3 expression in different molecular subtypes in the TCGA datasets. F. ROC curve analysis of the efficiency of HK3 expression in predicting the mesenchymal subtype in the TCGA datasets. The p value was determined by Student’s t test. The data are presented as the mean ± S.D. Significant results are presented as ns: nonsignificant, **p < 0.01, or ***p < 0.001